Stable serum resistance of Neisseria gonorrhoeae as an epidemiological marker.

Lectins agglutination test as an epidemiological marker for Neisseria gonorrhoeae.

Investigation of the Basis for Persistent Porin Serotypes of Neisseria Gonorrhoeae in Community Infections

Title of Thesis: Investigation of the Basis for Persistent Porin Serotypes of Neisseria gonorrhoeae in Community Infections Lotisha Erin Garvin, Master Degree, 2006 Thesis directed by: Ann Jerse, Ph. D. Associate Professor, Department of Microbiology and Immunology Uniformed Services University Neisseria gonorrhoeae porin (por), a major outer membrane protein, has been studied extensively in va...

Binding of Complement Factor H to Loop 5 of Porin Protein 1A: A Molecular Mechanism of Serum Resistance of Nonsialylated Neisseria gonorrhoeae

Neisseria gonorrhoeae isolated from patients with disseminated infection are often of the porin (Por1A) serotype and resist killing by nonimmune normal human serum. The molecular basis of this resistance (termed stable serum resistance) in these strains has not been fully defined but is not related to sialylation of lipooligosaccharide. Here we demonstrate that Por1A bearing gonococcal strains ...

Expression of AniA, the major anaerobically induced outer membrane protein of Neisseria gonorrhoeae, provides protection against killing by normal human sera.

Anaerobically grown Neisseria gonorrhoeae has previously been shown to have elevated serum resistance in the absence of exogenous CMP-N-acetylneuraminic acid or detectable sialylation. We hypothesized that the anaerobically induced gonococcal outer membrane protein AniA might have a role in this phenomenon, as it is the only known gonococcal protein that is absent under aerobic conditions. An N...

Antimicrobial susceptibility/resistance and NG-MAST characterisation of Neisseria gonorrhoeae in Belarus, Eastern Europe, 2010–2013

BACKGROUND Gonorrhoea and widely spread antimicrobial resistance (AMR) in its etiological agent Neisseria gonorrhoeae are major public health concerns worldwide. Gonococcal AMR surveillance nationally and internationally, to identify emerging resistance and inform treatment guidelines, is imperative for public health purposes. In 2009, AMR surveillance was initiated in Belarus, Eastern Europe b...